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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T2169 | Zebularine | NSC309132,4-Deoxyuridine | DNA Methyltransferase , Autophagy |
Zebularine (4-Deoxyuridine) is a DNA methylation inhibitor. Acts as a transition state analog inhibitor of cytidine deaminase by binding to the active size as covalent hydrates. It also inhibits cytidine deaminase (Ki: 2... | |||
T26972 | Cedazuridine | (4R)-2'-Deoxy-2',2'-difluoro-3,4,5,6-tetrahydrouridine | DNA Methyltransferase |
Cedazuridine ((4R)-2'-Deoxy-2',2'-difluoro-3,4,5,6-tetrahydrouridine) is an oral inhibitor of cytidine deaminase with antineoplastic properties. | |||
T60553 | Tetrahydrouridine dihydrate | ||
Tetrahydrouridine dihydrate (THU dihydrate) is a potent cytidine deaminase (CDA) inhibitor. Tetrahydrouridine dihydrate competitively blocks the active site of the enzyme more effectively than intrinsic cytidine. | |||
T60708 | Cedazuridine hydrochloride | ||
Cedazuridine (E7727) (Compound 7a) hydrochloride can be used for researching of cancer that is an orally active inhibitor of cytidine deaminase (CDA) (IC 50 = 0.4 μM) [1]. | |||
T17059 | Tetrahydrouridine | NSC 112907,NSC112907,NSC-112907 | DNA Methyltransferase |
Tetrahydrouridine (NSC-112907; THU) is a multidrug resistance modulator. It can be used in cancer treatment to make tumor cells more sensitive to radiation therapy. THU is a competitive cytidine deaminase(CDA) inhibitor ... |
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T19146 | 5,6-Dihydrouridine | Endogenous Metabolite | |
5,6-Dihydrouridine is a modified base found in conserved positions in the D-loop of tRNA in Eukaryota, Bacteria, and some Archaea. |
Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPH-01178 | CDA Protein, Human, Recombinant (His & Myc) | Human | E. coli |
CDA Protein, Human, Recombinant (His & Myc) is expressed in E. coli. | |||
TMPH-02908 | AICDA Protein, Mouse, Recombinant (His & Myc) | Mouse | E. coli |
Single-stranded DNA-specific cytidine deaminase. Involved in somatic hypermutation (SHM), gene conversion, and class-switch recombination (CSR) in B-lymphocytes by deaminating C to U during transcription of Ig-variable (... | |||
TMPH-01235 | APOBEC3A Protein, Human, Recombinant (His & SUMO) | Human | E. coli |
DNA deaminase (cytidine deaminase) with restriction activity against viruses, foreign DNA and mobility of retrotransposons. Exhibits antiviral activity against adeno-associated virus (AAV) and human T-cell leukemia virus... |